Controlled Tissue Penetration Systems

>Products> Controlled Tissue Penetration Systems

Controlled Force Means Better Outcomes

Human and animal tissues range from relatively soft skin to tougher muscle to hard bones. Diagnostic and medication delivery devices such as needles and lancets each require different forces to penetrate or access each of these tissues. Actuated Medical technology vibrates the sharp at an ideal frequency with sophisticated monitoring and closed–loop control. This allows controlled, low–force insertion of these sharps resulting in:

  • Reduced force and greater control while maintaining tactile sensations.

  • Minimized patient discomfort and stress.

  • Faster needle placement.

Incorporating this technology makes it easier to teach procedures and may allow less experienced clinicians to perform insertions.


GentleSharp is designed for pre-clinical veterinary and
laboratory research applications. It uses low–frequency
micro–vibrations to help needles glide more smoothly into
tissue. This requires less force, thereby reducing stress
during blood sampling procedures.

Compatible with standard hypodermic needles, GentleSharp
is available throughout the world for pre-clinical veterinary and
laboratory research applications only. Please visit
, email or call +1 814–355–0003 x117 for
pricing and purchase information.


GentleDispense uses a low power-activated, needle-free
patch system for transdermal delivery of large molecule
compounds. Potential delivery uses include drugs, peptides,
hydration, nutrition, and other compounds too large for
passive transport through the skin.

Please email or call +1 814–355–0003 x117 to discuss how
you might use this technology as a delivery mechanism for
your products.

Future Products

There are a wide variety of applications for Actuated Medical's controlled tissue penetration technology. Current projects include:

  • Smooth Insertion Spinal Needle – a system designed to enhance 27 gauge needle entry for regional anesthesia.

  • Low Insertion Force Epidural (LIFE) – a system designed to provide more controlled epidural needles entry for regional anesthesia.

  • OsteoAccess™ – a system designed to ease bone biopsy needle entry for compromised and difficult access patients.

For more information, please email Actuated Medical's customer support or call +1 814-355-0003 x117.


These works are/were partially supported by the National Institutes of Health: National Institute of General Medical Sciences SBIR grant Nos. GM085844 and GM100535; National Institute of Research Resources SBIR grant No. RR024943; National Cancer Institute SBIR grant No. CA139774; and National Institute on Aging SBIR grant No. AG037214. The views, opinions and/or findings contained in this work are those of Actuated Medical, Inc. and should not be construed as an official government position, policy or decision unless so designated by other documentation.

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